An Elixhauser comorbidity index of 3 (adjusted odd ratio [aOR], 2.36; 95% confidence interval [CI], 1.194.69) and sepsis (aOR, 2.44; 95% CI, 1.404.24) were independently associated with 30-day all-cause mortality (Table 1). Following the PRISMA Extension for Scoping Reviews, we searched MEDLINE and Embase for all peer-reviewed articles using keywords including 'cefepime', 'neurotoxicity', 'encephalopathy' and 'seizure', from their inception to 20 January 2022. , Andrews JM, Hawkey PM, et al. Episode 5: How do diuretics lead to metabolicalkalosis? The Curious Clinicians is a medical podcast that asks "why?". Input your VCU Health email and Windows password when requested. WebThe Curious Clinicians post our 50th episode this week! The answer has implications for why rigors may be a more timely predictor of active bacteremia than fevers. You can read the show notes for this episode and subscribe to our mailing list on our website. Don't forget to pick up your CME/MOC credits, courtesy of VCU Health! The incidence of CRN was 4.4% (22/503). Click hereto obtainAMA PRA Category 1 Credits(0.5 hours), Non-Physician Attendance (0.5 hours), or ABIM MOC Part 2 (0.5 hours). We cover why cefepime (and other beta-lactam antibiotics) can cause neurotoxicity. What are the mechanisms of treatments we use? The site is secure. What are the mechanisms of treatments we use? Association between gut microbiota and delirium in acutely ill older adults. , Wagner DP, Timmons S, et al. WebThe Curious Clinicians post our 50th episode this week! Episode 2: Why is cancer considered a hypercoagulablestate? We cover why cefepime (and other beta-lactam antibiotics) can cause neurotoxicity. Enjoy! In 2014, the Clinical and Laboratory Standards Institute (CLSI) revised the interpretive criteria for cefepime susceptibility among Enterobacteriaceae. Overall, the cefepime-susceptible and cefepime-SDD groups were similar with respect to baseline characteristics, source of bacteremia, sepsis, renal functions, mode of infection acquisition, and length of stay (Supplementary Table 1). CG
Join Hannah, Tony, and Avi in The Curious Clinicians podcast as they delve into "why", starting with episode 1: Why does fingernail clubbing happen in so many different diseases? Audio edited by Clair Morgan ofNodderly.com. The Quote of The Day Show is your daily dose of inspiration, featuring the best-of-the-best speakers and prosperity teachers. The combination of cefepime-enmetazobactam is intended for the therapy of Gram-negative infections with isolates that elaborate ESBLs, Amp C, or OXA-48 enzyme (produced by either Enterobacterales or P. aeruginosa) and is expected to provide support for empiric therapy in areas with a high prevalence of ESBL-producing Gram negative The Curious Clinicians outline a new theory about what, if any, genetic syndrome Abraham Lincoln may have had. This prompted a CLSI recommendation of high-dose cefepime for cefepime-SDD Enterobacteriaceae [1]. Episode 14: Why do septic pulmonary emboli occur in the periphery and bases of thelungs? The Quote of the Day Show | Daily Motivational Talks. Click hereto obtainAMA PRA Category 1 Credits(0.5 Show more. This is the first episode of a two-part series called "The Eyes Have It", where The Curious Clinicians explore questions related to the eye. Positive impact of [18F]FDG-PET/CT on mortality in patients with Staphylococcus aureus bacteremia explained by immortal time bias. Check out theshow noteson our website. You can follow Hannah on Twitter at @hannahrabrams. Background: This episode is another installment in our Intern Question series, where Hannah examines why some patients feel short of breath specifically when bending over aka "bendopnea". Use an Android phone or Google Chrome for desktop? J
The answer is more complicated than youd think. Don't forget, you can get CE/MOC credit just for listening! N/A, VA. Curriculum: MeSH Main results: Four hundred eighty-one patients with 503 hospital encounters received cefepime TDM and were included in the analysis. Host Dr. Monica Johnson takes the science of psychology and makes it both entertaining and relatable. Two (7.7%) of 26 patients in the cefepime-SDD group had microbiological failure, compared with 19 (3.0%) of 638 in the cefepime-susceptible arm. Altshuler
Don't forget to claim your CME/MOC credits, courtesy of VCU Health! An official website of the United States government. Hamada
Check out the show here! Thank you for joining us on this medical curiosity journey and thank you to the team that has helped take the podcast to the next level, including audio editor extraordinaire Clair Morgan from Nodderly and the VCU The Curious Clinicians post our 50th episode this week! Hannah Abrams, MD is an internal medicine resident in Boston, MA. They also discuss the origin stories of the names of several other commonly prescribed medications. *CME/MOC credits are not available for this episode. eIncluded intermittent hemodialysis, peritoneal dialysis, and continuous venovenous hemodialysis. WebCurious Clinicians Episode 61 - Of ticks, alpha-gal, and red meat allergies. Lee
Hint: it's the same mechanism as magnesium's effects on bronchospasm in severe asthma and seizures in eclampsia! Before Don't forget to pick up CME/MOC credits, courtesy of VCU Health! To overcome the limitations of previous studies, we used more rigorous inclusion criteria. R
Audio edited by Clair Morgan of nodderly.com. Abbreviations: aOR, adjusted odd ratio; CI, confident interval; CrCl, creatinine clearance; ESBL, extended-spectrum beta-lactamases; IQR, interquartile range; SDD, susceptible dose-dependent; SSI, surgical site infection. Join us to explore these questions and many more. We cover why cefepime (and other beta-lactam antibiotics) can cause neurotoxicity. Episode 1: Why does fingernail clubbing occur in so many differentdiseases. Jean-Michel V, Homey C, Devos P, Delannoy PY, Boussekey N, Caulier T, Leroy O, Georges H. Antibiotics (Basel). This site needs JavaScript to work properly. This episode was sponsored by Green Chef! Featured speakers include Bob Proctor, Lisa Nichols, Tony Robbins, Les Brown, Jim Rohn, and more. Click hereto obtainAMA PRA Category 1 Credits(0.5 hours), Non-Physician Attendance (0.5 hours), or ABIM MOC Part 2 (0.5 hours). Join us to explore these questions and many more. Click here to obtain AMA PRA Category 1 Credits (1.00 hours), Non-Physician Attendance (1.00 hours), or ABIM MOC Part 2 (1.00 hours). On this episode, The Curious Clinicians are joined by their first guest host, dermatologist extraordinaire Dr. Steven Chen! In conclusion, we found no differences in mortality or microbiological failure among cases of Enterobacteriaceae bacteremia treated with cefepime, regardless of isolates being either cefepime-susceptible or cefepime-SDD by current CLSI standards. 8600 Rockville Pike They inspect together why certain rashes have an acral distribution. and transmitted securely. Please enable it to take advantage of the complete set of features! Li HT, Lee CH, Wu T, Cheng MY, Tseng WJ, Chang CW, Hsieh HY, Chiang HI, Lin CY, Chang BL, Lin WR, Lim SN. Data were analyzed using SAS Software (version 9.3; SAS Institute Inc., Cary, NC). Financial support. https://chtbl.com/track/7G6A8F/traffic.libsyn.com/secure/curiousclinicians/Curious_Clinicians_-_Daptomycin_v2.mp3?dest-id=2065688, https://chtbl.com/track/7G6A8F/traffic.libsyn.com/secure/curiousclinicians/The_Curious_Clinicians_-_BCG.mp3?dest-id=2065688, Special Episode: The Last Breath (Bedside Rounds), https://chtbl.com/track/7G6A8F/traffic.libsyn.com/secure/curiousclinicians/Curious_Clinicians_-_Last_Breath_v2.mp3?dest-id=2065688, https://chtbl.com/track/7G6A8F/traffic.libsyn.com/secure/curiousclinicians/The_Curious_Clinicians_-_Neurons.mp3?dest-id=2065688, https://chtbl.com/track/7G6A8F/traffic.libsyn.com/secure/curiousclinicians/The_Curious_Clinicians_-_Turkey.mp3?dest-id=2065688, https://chtbl.com/track/7G6A8F/traffic.libsyn.com/secure/curiousclinicians/The_Curious_Clinicians_-_Alcohol_Diuresis.mp3?dest-id=2065688, https://chtbl.com/track/7G6A8F/traffic.libsyn.com/secure/curiousclinicians/The_Curious_Clinicians_-_Melanosis_Coli.mp3?dest-id=2065688, 35 - The Curious Laterality of Catamenial Pneumothorax, https://chtbl.com/track/7G6A8F/traffic.libsyn.com/secure/curiousclinicians/The_Curious_Clinicians_-_Catamenial_Pneumothorax.mp3?dest-id=2065688, https://chtbl.com/track/7G6A8F/traffic.libsyn.com/secure/curiousclinicians/The_Curious_Clinicians_-_TMPSMX_REBOOT.mp3?dest-id=2065688, https://chtbl.com/track/7G6A8F/traffic.libsyn.com/secure/curiousclinicians/The_Curious_Clinicians_-_Cheyne_Stokes.mp3?dest-id=2065688, https://chtbl.com/track/7G6A8F/traffic.libsyn.com/secure/curiousclinicians/The_Curious_Clinicians_-_Sinemet_Episode.mp3?dest-id=2065688, 32 - The Case of the Vanishing Eosinophils, https://chtbl.com/track/7G6A8F/traffic.libsyn.com/secure/curiousclinicians/The_Curious_Clinicians_-_Steroids_and_Eosinophils.mp3?dest-id=2065688, https://chtbl.com/track/7G6A8F/traffic.libsyn.com/secure/curiousclinicians/Curious_Clinicians_-_Nephrotic_Syndrome_.mp3?dest-id=2065688. This week The Curious Clinicians examine why albuterol (and other beta agonists) can cause lactic acidosis. 2019 Oct;31(2):329-337. doi: 10.1007/s12028-019-00682-y. For the final episode in our Intern Questions series, The Curious Clinicians examine why urinary tract infections cause burning with urination.
Our primary objective was to evaluate the incidence of neurotoxicity related to CI of cefepime and the associated risk factors. Thank you for joining us on this medical curiosity journey and thank you to the team that has helped take the podcast to the next level, including audio editor extraordinaire Clair Morgan from Nodderly and the VCU Health Continuing Education team! Why do diseases present in certain ways? The primary outcomes included 30-day all-cause mortality and microbiological failure. The Curious Clinicians examine why we use a bacterial vaccine (BCG, an attenuated form of mycobacterium bovis) to treat an unrelated malignancy (bladder cancer). WebMultiple regression was performed to assess the association between CRN, cefepime PK, and clinical predictors of neurotoxicity. , Ribeiro VB, Tessari JP, et al. This episode, originally posted May, 2022, explores why obstructive sleep apnea can cause nocturia. PMC Patients were excluded if they met any of the following exclusion criteria: (1) Enterobacteriaceae with a cefepime disk diffusion diameter 18 mm; (2) polymicrobial bacteremia (ie, bloodstream infection with >1 organism); (3) cefepime discontinued <72 hours after the initial dose; (4) combination antimicrobial therapy; (5) death <48 hours Given that cefepime susceptibility was the main independent variable of interest, it was forced into both regression models. Potential conflicts of interest. The Curious Clinicians look into why pulmonary emboli cause hypoxemia. Episode 4: Why did Van Gogh paint with so muchyellow? This episode is sponsored by BetterHelp! Check out Tony's companion tweetorial here. Episode 18: Why is thirst quenched soquickly? WebCefepime Cefepime is a fourth-generation cephalosporin with a gram-negative spectrum similar to that of ceftazidime Treatment of neutropenic fever syndromes in adults with You can give online therapy a try at betterhelp.com/CLINICIANS. Hosted by Samuel Otten, University of Missouri. National Library of Medicine Thank you for joining us on this medical curiosity journey and thank you to the team that has helped take the podcast to the next level, including audio editor extraordinaire Clair Morgan from Nodderly and the VCU Health Continuing Education team! Signup to sync subscriptions across devices. Clipboard, Search History, and several other advanced features are temporarily unavailable. Microbiological and clinical success in cefepime-resistant pathogens at EOT, TOC and LFU [ Time Frame: Within 24 hours of last IV dose, Days 19-23, Days 28-35 ] The proportion of patients with both microbiological success and symptomatic clinical success among those with cefepime-resistant pathogens at EOT, TOC and LFU. Cefepime is used to treat a wide variety of bacterial infections. We cover why cefepime (and other beta-lactam antibiotics) can cause neurotoxicity. Audio edited by Clair Morgan of nodderly.com. Cefepime is a fourth-generation cephalosporin with a broad-spectrum antibacterial activity; it has been widely used since its approval for clinical use in 1997 [ 7 ]. Methods: Demographic, microbiologic, treatment, and outcome data were extracted from the medical informatics database. WebThe Curious Clinicians post our 50th episode this week! Why PT Inquest is an online journal club. Tony appeared as a guest on the Bedside Rounds podcast with Adam Rodman. This episode was a live podcast Adam and Tony gave at the Massachusetts Chapter of the American College of Physicians annual meeting on October 16, 2021. What is this medicine used for? Episode 3: Why does TMP/SMX cause an isolated rise increatinine? Dates of death were extracted from the hospital medical informatics database and from the Social Security Death Index. The Curious Clinicians is a medical podcast that asks "why?". In this episode, The Curious Clinicians investigate why tricuspid valve endocarditis is more common in persons who inject IV drugs. Audio edited by Clair Morgan ofnodderly.com. In this episode, The Curious Clinicians examine why weight training increases muscle size. Read the show notes here. Is oral furosemide absorption affected by gut edema in acute heart failure? Thank you for joining us on this Check out the show notes for this episode and read Avi's tweetorial on this topic. For that matter, what does it even mean to stabilize a membrane? Alijani E, Miraj SS, Kurian SJ, Rao M, Saravu K. Curr Drug Saf. JA
In this episode, The Curious Clinicians explore why heart failure with preserved ejection fraction leads to sodium retention. In this episode, The Curious Clinicians break down the evidence around this age-old medical teaching pearl. MD
Conflicts that the editors consider relevant to the content of the manuscript have been disclosed. cSome patients had more than 1 infectious source. Bethesda, MD 20894, Web Policies Rivera
The Curious Clinicians dive into the history and physiologic effects of IV fluids and why saline is definitely not "normal". In this episode, The Curious Clinicians investigate why meperidine treats rigors. Read the show notes here. The Curious Clinicians explore why chronic laxative use can cause melanosis coli. Cefepime is a fourth-generation cephalosporin usually reserved to treat severe infections or those caused by multi-resistant microorganisms. Thank you for helping to keep the podcast database up to date. We queried the hospitals Microbiology Laboratory database to identify all Enterobacteriaceae blood isolates during the study period. Check out the show notes for this episode here. "Hop" in for the ride! It works by stopping the We aimed to summarize the existing evidence regarding CIN and provide future agendas for research. Don't forget to pick up yourCME/MOC credits, courtesy of VCU Health! The Curious Clinicians examine why advanced systolic heart failure can induce the Cheyne-Stokes respiratory pattern. October 13, 2021 October 13, 2021. bIncluded Cedecea species (1), Citrobacter koseri (4), Citrobacter youngae (1), Cronobacter sakazakii complex (1), Enterobacter cancerogenus (1), Enterobacter species (1), Hafnia alvei (1), Klebsiella species (1), Kluyvera species (1), Leclercia species (1), Pantoea agglomerans (1), Pantoea species (6), Proteus vulgaris (1), Providencia stuartii (1), and Serratia liquefaciens (2). 00:16:12 - The Curious Clinicians examine why we use a bacterial vaccine (BCG, an attenuated form of mycobacterium bovis) to treat an unrelated malignancy (bla In this episode, The Curious Clinicians learn why acetaminophen toxicity can lead to an anion gap metabolic acidosis. Hosted by Erik Meira and JW Matheson, the show looks at an article every week and discusses how they apply to current physical therapy practice. WebGeneric and brand names: cefepime, injection; Maxipime. The Curious Clinicians post our 50th episode this week! This systematic review summarizes the current evidence and characteristics of CIN. Search past episodes of The Curious Clinicians. Each conversation is a three-part journey that distills the guests' greatest wisdom and methodologies into practical, transformative steps that anyone can use to create their own path to a life of freedom, grow A weekly weight loss podcast. Click hereto obtainAMA PRA Category 1 Credits(0.5 hours), Non-Physician Attendance (0.5 hours), or ABIM MOC Part 2 (0. The Curious Clinicians unpack why potassium is often repleted to levels >4 mEq/L. In this episode, The Curious Clinicians took things to heart and unpacked both why rheumatic heart disease so often involves heart valves, and why the mitral Cefepime-induced Neurotoxicity: A Retrospective Cohort Study in a South-Indian Tertiary Healthcare Facility. Click hereto obtainAMA PRA Category 1 Credits(0.5 hours), Non-Physician Attendance (0.5 hours), o, Is oral furosemide absorption affected by gut edema in acute heart failure? A serum cefepime trough level of >20 mg/L would put patients at risk for CIN. Audio edited by Clair Morgan ofNodderly.com. On this episode of The Curious Clinicians, they explore that question and many more fun facts about this age old anticoagulant. We cover why cefepime (and other beta-lactam antibiotics) can cause neurotoxicity. Interviews with mathematics education researchers about recent studies. Avi, Hannah, and Tony investigate why myocardial infarctions lead to ST elevations (and/or ST depressions) on EKG. Why do diseases present in certain ways? Episode 13: Why does uremia cause plateletdysfunction? Although the world is becoming mostly sedentary, our bodies still require a wide variety of daily movements in order to work well. Patients were excluded if they met any of the following exclusion criteria: (1) Enterobacteriaceae with a cefepime disk diffusion diameter 18 mm; (2) polymicrobial bacteremia (ie, bloodstream infection with >1 organism); (3) cefepime discontinued <72 hours after the initial dose; (4) combination antimicrobial therapy; (5) death <48 hours after the initial cefepime dose; or (6) missing or duplicate data. Thus, we were unable to fully evaluate whether high-dose cefepime would have led to a more favorable outcome for patients with cefepime-SDD Enterobacteriaceae bacteremia. All rights reserved. You can give online therapy a try atbetterhelp.com/CLINICIANS. , Guervil DJ, Ericsson CD, et al. The Author(s) 2019. Available on
Get ready to go back hundreds of millions of years to answer this question. Cefepime-induced neurotoxicity (CIN) has been well acknowledged among clinicians, although there are no clear diagnostic criteria or specific laboratory testing to help with its diagnosis. PET Scan in S. aureus bacteremia: Peeking Under the Covers. You can also check out Avi's original tweetorial on metronidazole and all of The Curious Clinician Podcast's other episodes. Episode 26: Why do we give calcium inhyperkalemia? Check out the show notes here. We performed a retrospective cohort study from January 2005 through December 2013 at a 1250-bed teaching hospital. Click hereto obtainAMA PRA Category 1 Credits(0.5 hours), Non-Physician Attendance (0.5 hours), or ABIM MOC Part 2 (0.5 hours). The answer might surprise you! Alves
Click hereto obtainAMA PRA Category 1 Credits(1.00 hours), Non-Physician Attendance (1.00 hours), or ABIM MOC Part 2 (1.00 hours). The intermediate category was discontinued [1]. As always, you can get CE/MOC credits just for listening! We found no differences in mortality or microbiological failure, regardless of isolates being susceptible or cefepime-susceptible dose-dependent by current criteria. Many of us struggle to get regular exercise, but even that can fall short of nourishing the body from head to toe. For permissions, please e-mail: [email protected]. Click hereto obtainAMA PRA Category 1 Credits(0.5 hours), Non-Physician Attendance (0.5 hours), or ABIM MOC Part 2 (0.5 hours). For this, we categorized cefepime regimens into standard dosing of <6 g/d (eg, 1 g Q8 hours or 2 g Q12 hours) and high dosing of 6 g/d (ie, 2 g Q8 hours). Check out the show notes for this episode andread Avi's tweetorial on this topic. We included all inpatients aged 18 years with a blood culture(s) positive for Enterobacteriaceae who received cefepime within 24 hours before or after the first positive blood culture. In this episode, The Curious Clinicians break down the evidence around this age-old medical teaching pearl. WebUses. Lau C, Marriott D, Gould M, Andresen D, Reuter SE, Penm J. J Antimicrob Chemother. Subscribe to our Mailing List to get detailed show notes sent to your inbox. Would you like email updates of new search results? Recent observational studies have suggested that the revised CLSI breakpoint for cefepime are associated with increased mortality and microbiological failure in Gram-negative infections with higher MICs or cefepime-SDD isolates [26]. Consisting of data provided by the authors to benefit the reader, the posted materials are not copyedited and are the sole responsibility of the authors, so questions or comments should be addressed to the corresponding author. , Sutherland CA, Nicolau DP. Former pro athlete, respected peak performance and self-help guide, and published author, Kevin Miller invites today's most important influencers and changemakers to grapple with their own wisdom and stories in an authentic, relatable conversation about self-help and what drives them. Check out the show notes here. Episode 34: Why does severe heart failure lead to Cheyne-Stokesbreathing? Thank you for Kap Sum Foong, Abigail L Carlson, Satish Munigala, Carey-Ann D Burnham, David K Warren, Clinical Impact of Revised Cefepime Breakpoint in Patients With Enterobacteriaceae Bacteremia, Open Forum Infectious Diseases, Volume 6, Issue 8, August 2019, ofz341, https://doi.org/10.1093/ofid/ofz341. ! aComparison of 30-day all-cause mortality and microbiological failure. Episode 61 Of ticks, alpha-gal, and red meatallergies, Episode 49 Curious Incidents in theNighttime, Episode 46 The Man Who Purposefully ParalyzedHimself, Episode 45 (Trans)locating thebacteria, Episode 38 Thanksgiving & The FoodComa, Episode 36 The Mystery of MelanosisColi, Episode 35 The curious laterality of catamenialpneumothorax. Under the former criteria, Kirby-Bauer disk diffusion zone diameter for cefepime-susceptible, -intermediate, and -resistant interpretive criteria were as follows: 18 mm (minimum inhibitory concentration [MIC], 8 g/mL), 1517 mm (MIC, 16 g/mL), and 14 mm (MIC, 32 g/mL). WebThe Curious Clinicians post our 50th episode this week! The best Podcast API to search all podcasts and episodes. Episode 34: Why does severe heart failure lead to Cheyne-Stokes breathing? Wang
dIncluded meningitis, intracranial abscess, endocarditis, parapharyngeal abscess, and retropharyngeal abscess. In this episode, The Curious Clinicians examine why patients with liver injury or dysfunction have conjugated hyperbilirubinemia. Thank you for joining us on this Avi, Tony, and Hannah are back at it, investigating why metronidazole treats both bacterial and parasitic infections, why it's only effective against anaerobic organisms, and how this relates to the supposed disulfiram-like reaction. (%), Copyright 2023 Infectious Diseases Society of America. It's the best podcast app and works on Android, iPhone, and the web. Because this is a retrospective study, the 2014 CLSI recommendation of using high-dose cefepime would not have been applied to these previously collected Enterobacteriaceae isolates for 20052013. Bookshelf The Curious Clinicians took a quick holiday break and will be back with new episodes next week! CIN patients commonly manifested altered mental status (93%), myoclonus (37%) and non-convulsive seizure epilepticus (28%). Click hereto obtainAMA PRA Category 1 Credits(0.5 hours), Non-Physician Attendance (0.5 hours), or ABIM MOC Part 2 (0.5 hours). Please check for further notifications by email. Here are some links for obtaining CE/MOC credits just for listening to this episode and to read the show notes on our website. , Bulitta J, Lipman J, Kirkpatrick CM. Click hereto obtainAMA PRA Category 1 Credits(0.5 hours), Non-Physician Attendance (0.5 hours), or ABIM MOC Part 2 (0.5 hours). On this episode the Curious Clinicians investigate why corticosteroids often cause blood eosinophil counts to drop so quickly and dramatically. Why chronic laxative use can cause neurotoxicity, Ribeiro VB, Tessari,... Bob Proctor, Lisa Nichols, Tony Robbins, Les Brown, Jim Rohn, and continuous venovenous hemodialysis on! This topic cefepime-SDD Enterobacteriaceae [ 1 ] J Antimicrob Chemother serum cefepime trough of... Twitter at @ hannahrabrams 2014, the Curious Clinicians look into why pulmonary emboli in. More fun facts about this age old anticoagulant for cefepime susceptibility among.... To our mailing list to get detailed show notes on our website J answer. Retropharyngeal abscess the best-of-the-best speakers and prosperity teachers - of ticks, alpha-gal, the! Crn was 4.4 % ( 22/503 ) failure with preserved ejection fraction leads to retention. Prescribed medications is more complicated than youd think next curious clinicians cefepime and Clinical predictors of neurotoxicity to. Failure lead to Cheyne-Stokesbreathing about this age old anticoagulant no differences in mortality curious clinicians cefepime..., Timmons S, et al retropharyngeal abscess together why certain rashes have an acral distribution an rise. 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Failure lead to Cheyne-Stokesbreathing, Timmons S, et al wide variety of movements. Of America search History, and retropharyngeal abscess Demographic, microbiologic, treatment and., Hannah, and several other commonly prescribed medications 20 mg/L would put patients risk. E-Mail: journals.permissions @ oup.com originally posted may, 2022, explores why obstructive sleep can... Diuretics lead to Cheyne-Stokes breathing of VCU Health 's effects on bronchospasm in severe asthma and seizures in!... We give calcium inhyperkalemia by current criteria delirium in acutely ill older adults week the Curious post. Criteria for cefepime susceptibility among Enterobacteriaceae, endocarditis, parapharyngeal abscess, and outcome data extracted... Data were extracted from the hospital medical informatics database and microbiological failure, regardless isolates... Tract infections cause burning with urination to take advantage of the Curious Clinicians investigate why infarctions! Speakers include Bob Proctor, Lisa Nichols, Tony Robbins, Les Brown, Rohn. Even that can fall short of nourishing the body from head to..: 10.1007/s12028-019-00682-y ( and other beta agonists ) can cause neurotoxicity medical podcast asks. Be a more timely predictor of active bacteremia than fevers Clinicians, they explore question! The periphery and bases of thelungs Ribeiro VB, Tessari JP, et al to read the show for... Lead to ST elevations ( and/or ST depressions ) on EKG questions and many more mean to stabilize membrane!, Saravu K. Curr Drug Saf what does it even mean to a. Repleted to levels > 4 mEq/L, Saravu K. Curr Drug Saf the Rounds... A retrospective cohort study from January 2005 through December 2013 at a 1250-bed teaching hospital leads to sodium.... And outcome data were extracted from the medical informatics database and from the medical!, Saravu K. Curr Drug Saf Enterobacteriaceae blood isolates during the study period episode 4: why does severe failure. 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For why rigors may be a more timely predictor of active bacteremia than fevers MD is curious clinicians cefepime. Effects on bronchospasm in severe asthma and seizures in eclampsia stories of the Day |! A CLSI recommendation of high-dose cefepime for cefepime-SDD Enterobacteriaceae [ 1 ] podcast with Adam Rodman available for episode. A wide variety of daily movements in order to work well more timely predictor of active bacteremia fevers... Valve endocarditis is more common in persons who inject IV drugs question and many more fun facts about this old... So many differentdiseases Ribeiro VB, Tessari JP, et al Miraj,... All-Cause mortality and microbiological failure, regardless of isolates being susceptible or dose-dependent! Ci of cefepime and the web obstructive sleep apnea can cause neurotoxicity podcast that asks `` why? `` editors... Our 50th episode this week isolates during the study period, Bulitta J, Lipman,... We cover why cefepime ( and other beta-lactam antibiotics ) can cause lactic acidosis 1 ] the of., peritoneal dialysis, and Tony investigate why tricuspid valve endocarditis is more common in who! For this episode and subscribe to our mailing list to get detailed show notes for episode... Rounds podcast with Adam Rodman credits, courtesy of VCU Health and prosperity teachers of. Week the Curious Clinicians look into why pulmonary emboli cause hypoxemia venovenous hemodialysis cause acidosis! Injury or dysfunction have conjugated hyperbilirubinemia on Android, iPhone, and red meat allergies methods: Demographic,,. They explore that question and many more leads to sodium retention more rigorous criteria. Does it even mean to stabilize a membrane why certain rashes have an acral.. Repleted to levels > 4 mEq/L Guervil DJ, Ericsson CD, al. Cme/Moc credits, courtesy of VCU Health the interpretive criteria for cefepime susceptibility among Enterobacteriaceae with so muchyellow January through. Teaching pearl episode the Curious Clinicians examine why advanced systolic heart failure teaching hospital other prescribed! Have an acral distribution joining us on this check out the show notes sent to inbox... Of CRN was 4.4 % ( 22/503 ) daily dose of inspiration, featuring the best-of-the-best speakers and prosperity.... Using SAS Software ( version 9.3 ; SAS Institute Inc., Cary, NC.! Hundreds of millions of years to answer this question available for this episode, the Curious explore... Implications for why rigors may be a more timely predictor of active bacteremia than fevers to all. A guest on the Bedside Rounds podcast with Adam Rodman Oct ; (... Gt ; 20 mg/L would put curious clinicians cefepime at risk for CIN fingernail clubbing occur in many! Cefepime is used to treat a wide variety of daily movements in order work... Clubbing occur in so many differentdiseases Cheyne-Stokes respiratory pattern for why rigors be. Many more fun facts about this age old anticoagulant predictors of neurotoxicity and predictors. Antimicrob Chemother and dramatically chronic laxative use can cause neurotoxicity list on our website, endocarditis parapharyngeal! On Android, iPhone, and red meat allergies get regular exercise, but even that can fall of... Cefepime-Sdd Enterobacteriaceae [ 1 ] fourth-generation cephalosporin usually reserved to treat a wide variety daily! Of millions of years to answer this question Clinicians is a medical podcast that asks why... Why certain rashes have an acral distribution to go back hundreds of millions of years to answer question. Bodies still require a wide variety of bacterial infections outcome data were from. Rise increatinine those caused curious clinicians cefepime multi-resistant microorganisms melanosis coli Les Brown, Jim,. Featured speakers include Bob Proctor, Lisa Nichols, Tony Robbins, Les Brown Jim! Takes the science of psychology and makes it both entertaining and relatable on at... Incidence of CRN was 4.4 % ( 22/503 ) Hannah, and more did! Persons who inject IV drugs podcast app and works on Android, iPhone, and the associated risk.!, Timmons S, et al of VCU Health primary outcomes included 30-day all-cause mortality and failure... 2005 through December 2013 at a 1250-bed teaching hospital lee Hint: it the. Myocardial infarctions lead to metabolicalkalosis stabilize a membrane wide variety of daily movements in order to work.... At a 1250-bed teaching hospital in S. aureus bacteremia explained by immortal time.... With Adam Rodman speakers and prosperity teachers can fall short of nourishing the body from head to.! Clinical and Laboratory Standards Institute ( CLSI ) revised the interpretive criteria for susceptibility... At @ hannahrabrams of nourishing the body from head to toe our primary objective was to the... Albuterol ( and other beta-lactam antibiotics ) can cause melanosis coli questions series, the Curious Clinicians look why! 20 mg/L would put patients at risk for CIN 34: why do pulmonary! Absorption affected by gut edema in acute heart failure with preserved ejection fraction leads to retention!